Leptin inhibits rat hippocampal neurons via activation of large conductance calcium-activated K+ channels

Nat Neurosci. 2002 Apr;5(4):299-300. doi: 10.1038/nn824.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Calcium / metabolism
  • Carrier Proteins / metabolism
  • Cells, Cultured
  • Charybdotoxin / pharmacology
  • Hippocampus / cytology
  • Hippocampus / metabolism*
  • Humans
  • Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
  • Leptin / pharmacology*
  • Neurons / drug effects*
  • Neurons / metabolism
  • Patch-Clamp Techniques
  • Phosphatidylinositol 3-Kinases / metabolism
  • Potassium Channels, Calcium-Activated / antagonists & inhibitors
  • Potassium Channels, Calcium-Activated / metabolism*
  • Rats
  • Receptors, Cell Surface*
  • Receptors, Leptin
  • Tetraethylammonium / pharmacology
  • Tolbutamide / pharmacology

Substances

  • Carrier Proteins
  • Kcnma1 protein, rat
  • Large-Conductance Calcium-Activated Potassium Channel alpha Subunits
  • Leptin
  • Potassium Channels, Calcium-Activated
  • Receptors, Cell Surface
  • Receptors, Leptin
  • leptin receptor, human
  • Charybdotoxin
  • Tetraethylammonium
  • Tolbutamide
  • Phosphatidylinositol 3-Kinases
  • Calcium