The Cost of Antibiotic Resistance: Effect of Resistance Among Staphylococcus Aureus, Klebsiella Pneumoniae, Acinetobacter Baumannii, and Pseudmonas Aeruginosa on Length of Hospital Stay

Infect Control Hosp Epidemiol. 2002 Feb;23(2):106-8. doi: 10.1086/502018.

Abstract

To assess the effect of antimicrobial resistance on length of hospital stay, a case-control study compared infections due to four nosocomial pathogens. Significantly increased lengths of stay were associated with infections due to methicillin-resistant Staphylococcus aureus, extended-spectrum beta-lactamase-producing Klebsiella pneumoniae, and carbapenem-resistant Acinetobacter baumannii or Pseudomonas aeruginosa. Infections with resistant pathogens are associated with prolonged hospitalization.

MeSH terms

  • Acinetobacter / drug effects
  • Acinetobacter / pathogenicity
  • Aged
  • Bacterial Infections / economics
  • Bacterial Infections / epidemiology*
  • Case-Control Studies
  • Cross Infection / economics
  • Cross Infection / epidemiology*
  • Drug Resistance*
  • Hospital Mortality*
  • Humans
  • Klebsiella pneumoniae / drug effects
  • Klebsiella pneumoniae / pathogenicity
  • Length of Stay / economics*
  • New York City / epidemiology
  • Pseudomonas aeruginosa / drug effects
  • Pseudomonas aeruginosa / pathogenicity
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / pathogenicity