Diagnosis and management of astrocytomas, oligodendrogliomas and mixed gliomas: a review

Australas Radiol. 2001 Nov;45(4):472-82. doi: 10.1046/j.1440-1673.2001.00959.x.


Low-grade gliomas are a diverse group of neoplasms which, as the name implies, are thought to arise from glial cells. Common among this group are astrocytomas (low-grade astrocytoma; LGA), oligodendrogliomas and mixed gliomas. Among these, LGA is the commonest low-grade glioma and, occasionally, although incorrectly, the terms are used interchangeably. Advances in imaging technology have improved the accuracy of preoperative diagnosis. The management of low-grade gliomas is controversial. Recent evidence suggests that previously considered standard therapy (i.e. surgery plus radiotherapy) may not be in the patient's best interests. A review of the available published research concerning low-grade gliomas is therefore timely.

Publication types

  • Review

MeSH terms

  • Astrocytoma / diagnosis
  • Astrocytoma / therapy*
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / therapy*
  • Disease Progression
  • Glioma / diagnosis
  • Glioma / therapy*
  • Humans
  • Magnetic Resonance Imaging
  • Oligodendroglioma / diagnosis
  • Oligodendroglioma / therapy*
  • Prognosis
  • Telencephalon / pathology*
  • Tomography, X-Ray Computed