Mechanisms of subcellular mRNA localization

Cell. 2002 Feb 22;108(4):533-44. doi: 10.1016/s0092-8674(02)00651-7.


Localization of RNA is a widespread and efficient way to target gene products to a specific region of a cell or embryo. This strategy of posttranscriptional gene regulation utilizes a variety of distinct mechanisms to regulate the movement and anchoring of different transcripts.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Active Transport, Cell Nucleus / physiology
  • Animals
  • Cytoskeleton / metabolism
  • Fungal Proteins / metabolism
  • Gene Expression Regulation / physiology*
  • Models, Biological
  • RNA Processing, Post-Transcriptional
  • RNA, Messenger / metabolism*
  • RNA-Binding Proteins / metabolism
  • Trans-Activators / metabolism


  • Fungal Proteins
  • RNA, Messenger
  • RNA-Binding Proteins
  • Trans-Activators