Exploiting genome sequence: predictions for mechanisms of Campylobacter chemotaxis

Trends Microbiol. 2002 Apr;10(4):155-9. doi: 10.1016/s0966-842x(02)02323-5.


The genome sequence of Campylobacter jejuni NCTC 11168 reveals the presence of orthologues of the chemotaxis genes cheA, cheW, cheV, cheY, cheR and cheB, ten chemoreceptor genes and two aerotaxis genes. The presence of cheV and a response regulator domain in CheA, combined with the absence of a cheZ gene and the lack of a response regulator domain in CheB, reveals significant differences in the C. jejuni chemotaxis system compared with that found in other bacteria.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics*
  • Base Sequence
  • Campylobacter jejuni / genetics*
  • Campylobacter jejuni / physiology*
  • Chemotaxis / genetics*
  • Escherichia coli / genetics
  • Escherichia coli / physiology
  • Escherichia coli Proteins
  • Gene Expression Regulation, Bacterial
  • Genome, Bacterial*
  • Histidine Kinase
  • Membrane Proteins / genetics
  • Methyl-Accepting Chemotaxis Proteins
  • Signal Transduction


  • Bacterial Proteins
  • Escherichia coli Proteins
  • Membrane Proteins
  • Methyl-Accepting Chemotaxis Proteins
  • cheY protein, E coli
  • Histidine Kinase
  • cheA protein, E coli