Primary Sjögren's syndrome initially manifested by optic neuritis: MRI findings

Neuroradiology. 2002 Apr;44(4):338-41. doi: 10.1007/s00234-001-0730-6. Epub 2002 Feb 16.


We herein describe the MRI findings in a patient clinically diagnosed with primary Sjögren's syndrome (SjS) initially manifested by retrobulbar optic neuritis. A 63-year-old woman suddenly had left ocular pain and progressive visual disturbance. MR T2-weighted images revealed hyperintensity in the left optic nerve, with swelling. Contrast-enhanced T1-weighted images showed no abnormal enhancement. Follow-up MRI 6 months after admission revealed no significant changes in the affected optic nerve. To our knowledge, optic neuritis as a complication of SjS has been reported in ten patients [1, 2, 3, 4, 5, 6] and MRI findings in only one of them [6]. We thought MR images were useful for visualizing optic nerve involvement in SjS and observing its course.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Optic Nerve / pathology
  • Optic Neuritis / complications
  • Optic Neuritis / diagnosis*
  • Sjogren's Syndrome / complications*
  • Sjogren's Syndrome / diagnosis