Definitions of cytomegalovirus infection and disease in transplant recipients

Clin Infect Dis. 2002 Apr 15;34(8):1094-7. doi: 10.1086/339329. Epub 2002 Mar 11.


Cytomegalovirus (CMV) infection and disease are important causes of morbidity and mortality among transplant recipients. For the purpose of developing consistent reporting of CMV in clinical trials, definitions of CMV infection and disease were developed and published. This study seeks to update the definitions of CMV on the basis of recent developments in diagnostic techniques, as well as to add to these definitions the concept of indirect effects caused by CMV.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cytomegalovirus / isolation & purification*
  • Cytomegalovirus Infections / blood
  • Cytomegalovirus Infections / diagnosis*
  • Cytomegalovirus Infections / metabolism
  • Cytomegalovirus Infections / mortality
  • Humans
  • Immunocompromised Host
  • Transplantation / adverse effects*