Manipulating the folding pathway of delta F508 CFTR using chemical chaperones

Methods Mol Med. 2002;70:267-75. doi: 10.1385/1-59259-187-6:267.
No abstract available

MeSH terms

  • Animals
  • Blotting, Western
  • Cell Line
  • Cyclic AMP / metabolism
  • Cystic Fibrosis Transmembrane Conductance Regulator / chemistry*
  • Cystic Fibrosis Transmembrane Conductance Regulator / genetics*
  • Cystic Fibrosis Transmembrane Conductance Regulator / metabolism
  • Epithelial Cells / metabolism
  • Gene Deletion
  • Humans
  • Mutation*
  • Plasmids / metabolism
  • Protein Folding
  • Transfection / methods*
  • Water / metabolism

Substances

  • CFTR protein, human
  • Water
  • Cystic Fibrosis Transmembrane Conductance Regulator
  • Cyclic AMP