Early thrombolysis in stroke due to basilar artery occlusion

Neurol Sci. 2001 Oct;22(5):399-402. doi: 10.1007/s100720100072.

Abstract

Basilar artery occlusion is usually associated with a poor prognosis. Nevertheless, intra-arterial thrombolysis has been shown to improve clinical outcome in selected cases. We report the case of a 29-year-old patient who suffered a severe ischemic stroke due to basilar artery occlusion and who was treated with intra-arterial thrombolysis within 3 h of symptoms onset; treatment was followed by an almost full functional recovery. The young age of the patient, short segment occlusion in the middle tract of the artery, good collateral supply, and early recanalization may account for the favorable prognosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticoagulants / pharmacology
  • Basilar Artery / diagnostic imaging
  • Basilar Artery / pathology
  • Brain Stem / blood supply
  • Brain Stem / diagnostic imaging
  • Brain Stem / pathology
  • Brain Stem Infarctions / diagnostic imaging
  • Brain Stem Infarctions / drug therapy*
  • Brain Stem Infarctions / pathology
  • Drug Administration Schedule
  • Fibrinolytic Agents / therapeutic use*
  • Heparin / therapeutic use
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Recovery of Function / drug effects
  • Thrombolytic Therapy / methods*
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ultrasonography, Doppler, Transcranial
  • Urokinase-Type Plasminogen Activator / therapeutic use
  • Vertebrobasilar Insufficiency / diagnostic imaging
  • Vertebrobasilar Insufficiency / drug therapy*
  • Vertebrobasilar Insufficiency / pathology
  • Warfarin / pharmacology

Substances

  • Anticoagulants
  • Fibrinolytic Agents
  • Warfarin
  • Heparin
  • Urokinase-Type Plasminogen Activator