Metastatic basal cell carcinoma with squamous appearances in the naevoid basal cell carcinoma syndrome

Br J Plast Surg. 1975 Oct;28(4):331-4. doi: 10.1016/0007-1226(75)90045-4.


A patient with the naevoid basal cell carcinoma syndrome developed a secondary carcinomatous deposit in the pelvis. Persisting tumour in the skull and the secondary deposit in the pelvis contained areas of squamous differentiation. This confirms that the appearances of baso-squamous (or transitional or metatypical-cell) carcinoma can develop from typical basal cell carcinoma which had not been subjected to radiotherapy or to more than one surgical excision.

Publication types

  • Case Reports

MeSH terms

  • Bone Cysts*
  • Carcinoma, Basal Cell* / pathology
  • Carcinoma, Basosquamous* / pathology
  • Head and Neck Neoplasms / pathology
  • Humans
  • Jaw Diseases*
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Ribs / abnormalities*
  • Skin Neoplasms / pathology
  • Syndrome