Evaluation of the Abbott LCx quantitative assay for measurement of human immunodeficiency virus RNA in plasma

J Clin Microbiol. 2002 Apr;40(4):1518-21. doi: 10.1128/jcm.40.4.1518-1521.2002.

Abstract

Plasma human immunodeficiency virus RNA in 491 clinical specimens was measured by LCx. There was a strong correlation with the results provided by other methods (r(2) values of 0.93 with Cobas-Monitor version 1.5 and of 0.95 with Quantiplex version 3.0). However, values were uniformly higher with LCx than with Quantiplex when non-B subtypes were tested.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • HIV Infections / diagnosis*
  • HIV Infections / virology*
  • HIV-1 / genetics
  • HIV-1 / isolation & purification*
  • Humans
  • Ligase Chain Reaction / methods*
  • RNA, Viral / blood*
  • Reagent Kits, Diagnostic
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Viral Load

Substances

  • RNA, Viral
  • Reagent Kits, Diagnostic