Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity

Phytomedicine. 2002 Jan;9(1):3-8. doi: 10.1078/0944-7113-00078.


The green tea extract AR25 is an 80% ethanolic dry extract standardized at 25% catechins expressed as epigallocatechin gallate (EGCG). In vitro, green tea extract AR25 exerts a direct inhibition of gastric and pancreatic lipases and a stimulation of thermogenesis. In an open study, the effects of extract AR25 were evaluated in moderately obese patients. After 3 months, body weight was decreased by 4.6% and waist circumference by 4.48%. These results suggest the green tea extract AR25 to be a natural product for the treatment of obesity, which exerts its activity by several ways: inhibition of lipases and stimulation of thermogenesis.

Publication types

  • Clinical Trial
  • Multicenter Study

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Body Mass Index
  • Camellia sinensis
  • Chromatography, High Pressure Liquid
  • Female
  • France
  • Humans
  • Male
  • Middle Aged
  • Obesity / drug therapy*
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / therapeutic use*
  • Tea*


  • Plant Extracts
  • Tea
  • green tea extract AR25