A role for actin-driven secretion in auxin-induced growth

Protoplasma. 2002 Feb;219(1-2):72-81. doi: 10.1007/s007090200007.


In epidermal cells of Zea mays coleoptiles, actin microfilaments are organized in fine strands during cell elongation, but are bundled in response to signals that inhibit growth. This bundling response is accompanied by an increased membrane association of extracted actin. Brefeldin A, an inhibitor of vesicle secretion, increases the membrane association of actin, causes a bundling of cortical actin microfilaments, and reduces the sensitivity of cell elongation to auxin. A model is proposed where auxin controls the dynamics of an actin subpopulation that guides vesicles loaded with components of the auxin-signaling machinery towards the cell poles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actin Cytoskeleton / chemistry
  • Actin Cytoskeleton / drug effects
  • Actin Cytoskeleton / metabolism
  • Actins / metabolism*
  • Brefeldin A / pharmacology
  • Cell Division / drug effects
  • Centrifugation
  • Cotyledon / cytology
  • Cotyledon / drug effects
  • Cotyledon / genetics
  • Cotyledon / metabolism
  • Indoleacetic Acids / pharmacology*
  • Models, Biological
  • Secretory Vesicles / drug effects*
  • Secretory Vesicles / metabolism
  • Signal Transduction / drug effects
  • Zea mays / cytology*
  • Zea mays / drug effects*
  • Zea mays / growth & development
  • Zea mays / metabolism


  • Actins
  • Indoleacetic Acids
  • Brefeldin A