Prevalence and progression of myopic retinopathy in an older population

Ophthalmology. 2002 Apr;109(4):704-11. doi: 10.1016/s0161-6420(01)01024-7.


Objective: To determine the prevalence and progression of myopic retinopathy in an older community-based population sample.

Design: Population-based epidemiologic study.

Participants: Eligible residents aged 49 years or older (n = 3654) who attended the Blue Mountains Eye Study, west of Sydney, Australia.

Methods: Participants had a detailed eye examination including measurement of logarithm of the minimum angle of resolution (logMAR) visual acuity, standardized refraction, and retinal stereophotography. All patients were invited to attend follow-up examinations after 5 years.

Main outcome measures: Myopic retinopathy was defined to include staphyloma, lacquer cracks, Fuchs' spot and myopic chorioretinal atrophy. beta-peripapillary atrophy was assessed separately.

Results: Signs of myopic retinopathy were found in 67 eyes from 44 participants (1.2%), a prevalence of 1.4% in women and 1.0% in men; this increased from 1% in right eyes with myopia <3 diopters to over 50% in right eyes with myopia > or =9 diopters. There was a nonsignificant age-related trend in prevalence. The average spherical equivalent refraction was -6.1 diopters and the average visual acuity was 20/40 in eyes with myopic retinopathy. Visual impairment (<20/40) was present in 38.8% of affected eyes. Myopic retinopathy was bilateral in 52% of cases. Staphyloma was present in 26 participants (0.7%), bilateral in 35%, with a strong concordance of staphyloma location. Lacquer cracks were seen in 8 participants (0.2%), Fuchs' spot in 3 (0.1%), and chorioretinal atrophy in 7 (0.2%). Forty-six eyes (68.7%) with myopic retinopathy were reexamined after 5 years; 8.7% had new or increased numbers of lacquer cracks and 15.2% had new or expanded areas of chorioretinal atrophy. In those eyes developing lacquer cracks or chorioretinal atrophy, best-corrected visual acuity decreased by a mean of two LogMAR lines.

Conclusions: This study documented the age and sex-specific prevalence of myopic retinopathy and 5-year progression in an older white population.

MeSH terms

  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Disease Progression
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myopia / epidemiology*
  • Myopia / physiopathology
  • New South Wales / epidemiology
  • Photography
  • Prevalence
  • Refraction, Ocular
  • Retinal Diseases / epidemiology*
  • Retinal Diseases / physiopathology
  • Sex Distribution
  • Urban Population / statistics & numerical data
  • Visual Acuity