Comparative results of coronary intervention in patients with variant angina versus those with non-variant angina

Jpn Heart J. 2001 Nov;42(6):657-67. doi: 10.1536/jhj.42.657.


Coronary angioplasty is reported to be feasible and safe in patients with coronary spasm and fixed stenosis. However, the long-term results are not positive. We compared the results of coronary angioplasty in 20 patients with variant angina versus 17 patients with non-variant angina among 231 consecutive patients with vasospastic angina. Coronary angioplasty was performed successfully in all 37 patients without any complications. Stenting for coronary dissection or recoil was performed in 8 patients, directional coronary atherectomy was selected for ostial lesion of left anterior descending coronary artery stenosis in 2 patients, and standard balloon angioplasty was performed in 27 patients. There were no clinical differences between the two groups. The restensois rate in patients with variant angina was similar to that in patients with non-variant angina (30% vs 29%, ns). There was no relationship between the provoked spasm and restenosis. During the follow-up period, no major complications were observed in patients with variant angina or those with non-variant angina. In conclusion, full medication with calcium channel antagonists and isosorbide dinitrate, and treatment by coronary angioplasty including the use of new devices, were useful treatments for patients with coronary vasospasm and significant organic stenosis. There was no difference concerning the results of coronary intervention between the patients with variant angina and those with non-variant angina.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Angina Pectoris / therapy*
  • Angina Pectoris, Variant / therapy*
  • Angioplasty, Balloon, Coronary*
  • Coronary Angiography
  • Coronary Restenosis / epidemiology*
  • Coronary Vasospasm / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Stents