Aging: from radiant youth to an abrupt end

Joel H Rothman

doi:10.1016/s0960-9822(02)00780-7

Aging: from radiant youth to an abrupt end

Curr Biol. 2002 Apr 2;12(7):R239-41. doi: 10.1016/s0960-9822(02)00780-7.

Author

Joel H Rothman¹

Affiliation

¹ Department of MCD Biology, University of California, Santa Barbara, California 93106, USA. rothman@lifesci.ucsb.edu

PMID: 11937038
DOI: 10.1016/s0960-9822(02)00780-7

Abstract

A gene that controls growth rate, radiation resistance and lifespan in the nematode Caenorhabditis elegans has been found to encode a homologue of a yeast telomere maintenance factor, raising the possibility that checkpoint control, telomere maintenance and aging may be linked in unanticipated ways.

Publication types

Review

MeSH terms

Aging / metabolism*
Animals
Caenorhabditis elegans / metabolism*
Caenorhabditis elegans Proteins / genetics
Caenorhabditis elegans Proteins / metabolism*
Telomere / physiology*
Telomere-Binding Proteins*

Substances

Caenorhabditis elegans Proteins
Telomere-Binding Proteins
clk-2 protein, C elegans