Aging: from radiant youth to an abrupt end

Curr Biol. 2002 Apr 2;12(7):R239-41. doi: 10.1016/s0960-9822(02)00780-7.


A gene that controls growth rate, radiation resistance and lifespan in the nematode Caenorhabditis elegans has been found to encode a homologue of a yeast telomere maintenance factor, raising the possibility that checkpoint control, telomere maintenance and aging may be linked in unanticipated ways.

Publication types

  • Review

MeSH terms

  • Aging / metabolism*
  • Animals
  • Caenorhabditis elegans / metabolism*
  • Caenorhabditis elegans Proteins / genetics
  • Caenorhabditis elegans Proteins / metabolism*
  • Telomere / physiology*
  • Telomere-Binding Proteins*


  • Caenorhabditis elegans Proteins
  • Telomere-Binding Proteins
  • clk-2 protein, C elegans