Genital herpes simplex virus type 1 infection: new fields for an old acquaintance?

Intervirology. 2002;45(1):2-5. doi: 10.1159/000050080.


Herpes simplex virus (HSV)-2 is the principal agent of chronic remittent genital herpes. Worldwide, only 10-20% of genital isolates are HSV-1. Studies from the British Isles and Scandinavia indicate, however, that HSV-1 is responsible for a significant proportion or even the majority of first clinical episodes of genital herpes in young women. Actual data show that a trend towards genital HSV-1 infections may also hold true for Germany. This article summarizes possible reasons for and consequences of the observed changes in the epidemiology of genital HSV infections.

Publication types

  • Review

MeSH terms

  • Adult
  • Female
  • Herpes Genitalis / epidemiology*
  • Herpes Genitalis / virology
  • Herpesvirus 1, Human*
  • Humans
  • Sexually Transmitted Diseases, Viral / epidemiology*
  • Sexually Transmitted Diseases, Viral / virology