Progress of visual dysfunction in Parkinson's disease

Acta Neurol Scand. 2002 Apr;105(4):256-60. doi: 10.1034/j.1600-0404.2002.1o154.x.


Studies on progression of Parkinson's disease (PD) mainly focus on the nigrostriatal dopaminergic decline, but not on the visual system. We determined progression of (i) disturbed color vision, assessed with the Farnsworth-Munsell 100 Hue test (FMT) and (ii) intensity of PD in 18 patients. Significant differences occurred between (i) initial FMT error scores and follow-up results 3 years later (P=0.002) and analogously (ii) scored intensity of PD (P=0.002). A relation between computed differences of FMT error scores and rated activities of daily living appeared. Deterioration of color vision progresses in PD.

MeSH terms

  • Color Perception Tests
  • Color Perception*
  • Color Vision Defects / classification
  • Color Vision Defects / diagnosis*
  • Color Vision Defects / etiology*
  • Color Vision Defects / physiopathology
  • Disease Progression
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Parkinson Disease / complications*
  • Parkinson Disease / physiopathology*