Cascade radical reactions catalyzed by a Pd/light system: cyclizative multiple carbonylation of 4-alkenyl iodides

Ilhyong Ryu; Sergio Kreimerman; Fumikazu Araki; Satoshi Nishitani; Yoji Oderaotoshi; Satoshi Minakata; Mitsuo Komatsu

doi:10.1021/ja017315e

Cascade radical reactions catalyzed by a Pd/light system: cyclizative multiple carbonylation of 4-alkenyl iodides

J Am Chem Soc. 2002 Apr 17;124(15):3812-3. doi: 10.1021/ja017315e.

Authors

Ilhyong Ryu¹, Sergio Kreimerman, Fumikazu Araki, Satoshi Nishitani, Yoji Oderaotoshi, Satoshi Minakata, Mitsuo Komatsu

Affiliation

¹ Department of Chemistry, Faculty of Arts and Sciences, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan. ryu@ms.cias.osakafu-u.ac.jp

PMID: 11942801
DOI: 10.1021/ja017315e

Abstract

Cascade reactions of 4-alkenyl iodides, involving a carbonylation-cyclization-carbonylation sequence, were accomplished by a hnu/Pd system. The stereochemical outcomes suggest that radical carbonylation and subsequent acyl radical cyclization may be involved in this reaction.