BSD: a novel domain in transcription factors and synapse-associated proteins

Trends Biochem Sci. 2002 Apr;27(4):168-70. doi: 10.1016/s0968-0004(01)02042-4.


This article describes a novel domain, BSD, that is present in basal transcription factors, synapse-associated proteins and several hypothetical proteins. It occurs in a variety of species ranging from primal protozoan to human. The BSD domain is characterized by three predicted alpha helices, which probably form a three-helical bundle, as well as by conserved tryptophan and phenylalanine residues, located at the C terminus of the domain.

MeSH terms

  • Amino Acid Motifs*
  • Amino Acid Sequence
  • Animals
  • Humans
  • Molecular Sequence Data
  • Neuropeptides / chemistry*
  • Sequence Homology, Amino Acid
  • Transcription Factors / chemistry*


  • Neuropeptides
  • Transcription Factors