Economic Evaluation of Kidney Transplantation Versus Hemodialysis in Patients With End-Stage Renal Disease in Hungary

Prog Transplant. 2001 Sep;11(3):188-93. doi: 10.7182/prtr.11.3.c065760410446707.


Background: Kidney transplantation is generally acknowledged as the more clinically effective and more cost-effective option in managing patients with end-stage renal disease, compared with dialysis. This study looked for confirmatory evidence in a Hungarian population.

Methods: Patients (n = 242) with end-stage renal disease who received cadaveric kidney transplantation during 1994 were followed up for 3 years. They were compared with patients (n = 840) receiving hemodialysis who were on a waiting list for transplantation. Data were collected retrospectively. Treatments were compared for clinical efficacy and for cost-effectiveness.

Results: At month 36, the standard mortality hazard function was 3.5 times higher in the group receiving hemodialysis (P < .0001) than in the transplant recipients. Average treatment costs per patient over the 3 years were also significantly higher (P < .0001) in the hemodialysis group than in the group than received transplants. The cost of 1 year gained by transplantation was significantly less (P < .0001) than the cost associated with hemodialysis.

Conclusions: Compared with hemodialysis, kidney transplantation provides greater survival benefits to patients with end-stage renal disease, at less cost.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Cost-Benefit Analysis
  • Female
  • Health Care Costs / statistics & numerical data*
  • Humans
  • Hungary / epidemiology
  • Kidney Failure, Chronic / economics*
  • Kidney Failure, Chronic / mortality
  • Kidney Failure, Chronic / surgery
  • Kidney Failure, Chronic / therapy*
  • Kidney Transplantation / economics*
  • Male
  • Middle Aged
  • Odds Ratio
  • Renal Dialysis / economics*
  • Retrospective Studies
  • Survival Analysis
  • Treatment Outcome