Abstract
Anterograde tracing techniques combined with postembedding immunocytochemical staining were used to determine the gamma amino butyric acid (GABA) content of pretectogeniculate (PT-LGN) terminals and their postsynaptic targets. The results provide evidence that PT-LGN terminals are GABAergic and that they contact GABAergic interneurons. These results corroborate previous anatomical studies and support the idea that the PT-LGN projection functions to disinhibit thalamocortical cells in the dorsal lateral geniculate nucleus.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Cats
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Female
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Geniculate Bodies / physiology
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Geniculate Bodies / ultrastructure*
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Interneurons / physiology
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Interneurons / ultrastructure*
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Neurons, Afferent / chemistry
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Neurons, Afferent / physiology
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Presynaptic Terminals / physiology
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Presynaptic Terminals / ultrastructure*
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Superior Colliculi / physiology
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Superior Colliculi / ultrastructure*
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Visual Pathways / physiology
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Visual Pathways / ultrastructure
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gamma-Aminobutyric Acid / physiology*