CT and MR features of nasopharyngeal carcinoma in children and young adults

Clin Radiol. 2002 Mar;57(3):205-10. doi: 10.1053/crad.2001.0731.

Abstract

Aim: To clarify CT and MR features of nasopharyngeal carcinoma (NPC) in children and young adults.

Method: CT and MR findings of 13 patients (30 years old or younger) with a histopathologic diagnosis of NPC were reviewed.

Results: Skull base invasion (12/13), lymphadenopathy (10/13), and infiltrative growth (8/8) were common findings. The signal intensity of tumours was slightly higher than that of muscles in six cases and isointense to that of muscles in two cases on T1-weighted images; it was higher than that of muscle and lower than that of cerebellar grey matter on T2-weighted images in all cases. Internal signals were homogeneous in both pre- and post-Gd-enhanced MR images in all cases.

Conclusions: Despite its rarity in this age group, NPC should be included in a differential diagnosis when CT and MR imaging reveal these features.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Lymphatic Metastasis
  • Magnetic Resonance Imaging*
  • Male
  • Nasopharyngeal Neoplasms / diagnosis*
  • Nasopharyngeal Neoplasms / diagnostic imaging
  • Nasopharyngeal Neoplasms / pathology
  • Neoplasm Invasiveness / diagnosis
  • Neoplasm Invasiveness / diagnostic imaging
  • Retrospective Studies
  • Skull / pathology
  • Tomography, X-Ray Computed*