Helicobacter and gastric MALT lymphoma

Gut. 2002 May;50 Suppl 3(Suppl 3):III19-24. doi: 10.1136/gut.50.suppl_3.iii19.


Helicobacter pylori infection is a pre-MALT lymphoma condition. H pylori eradication leads to complete remission in 80% of low grade stage E1 lymphomas, with a yearly recurrence rate of approximately 5%. The possibility for complete remission in high grade lymphomas needs to be investigated in prospective studies. In addition, the significance of persistent B cell monoclonality (stable disease? danger of relapse? regression of monoclonality?) needs to be investigated in follow up studies.

Publication types

  • Review

MeSH terms

  • Animals
  • Biopsy
  • Disease Progression
  • Gastric Mucosa / microbiology
  • Gastric Mucosa / pathology
  • Gastritis / drug therapy
  • Gastritis / microbiology*
  • Helicobacter Infections / complications*
  • Helicobacter Infections / drug therapy
  • Helicobacter pylori*
  • Humans
  • Lymphoma, B-Cell, Marginal Zone / drug therapy
  • Lymphoma, B-Cell, Marginal Zone / microbiology*
  • Lymphoma, B-Cell, Marginal Zone / pathology
  • Remission Induction
  • Stomach Neoplasms / drug therapy
  • Stomach Neoplasms / microbiology*
  • Stomach Neoplasms / pathology