Dopamine effects on pulmonary artery pressure in hypotensive preterm infants with patent ductus arteriosus

J Pediatr. 2002 Mar;140(3):373-5. doi: 10.1067/mpd.2002.123100.


We investigated the effects of dopamine on pulmonary artery pressure in 18 ventilated hypotensive preterm neonates by using the flow characteristics of the ductal shunt. Dopamine has variable effects on pulmonary/systemic mean arterial pressure ratio with half the neonates showing an increase in pulmonary pressure relative to systemic pressure.

MeSH terms

  • Blood Pressure / drug effects*
  • Dopamine / pharmacology*
  • Ductus Arteriosus, Patent / physiopathology*
  • Echocardiography, Doppler
  • Hemodynamics
  • Humans
  • Hypotension / drug therapy*
  • Hypotension / physiopathology
  • Infant, Newborn
  • Infant, Premature
  • Prospective Studies
  • Pulmonary Artery / drug effects*
  • Vasoconstrictor Agents / pharmacology*


  • Vasoconstrictor Agents
  • Dopamine