Chemo-ablation of the prostate with dehydrated alcohol for the treatment of prostatic obstruction

J Urol. 2002 May;167(5):2100-3; discussion 2103-4.

Abstract

Purpose: We confirmed clinically whether chemo-ablation of the prostate with absolute ethanol may be an innovative transurethral approach for the relief of obstructive benign prostatic hyperplasia.

Methods: Using the InjecTx endoscopic device (Injectx Inc., San Jose, California) an initial cohort of 15 patients, including 13 who have now been followed more than 1 year, underwent elective transurethral chemo-ablation of the prostate.

Results: Preoperative and postoperative comparisons of the American Urological Association symptom score, maximum urine flow rate and prostatic volume reveal significant improvement with minimal discomfort and no major complication.

Conclusions: The InjecTx technique proved encouragingly successful in this initial small-scale clinical trial.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cystoscopes
  • Equipment Design
  • Ethanol / administration & dosage*
  • Humans
  • Injections, Intralesional
  • Male
  • Middle Aged
  • Prostatic Hyperplasia / drug therapy*
  • Treatment Outcome
  • Urinary Bladder Neck Obstruction / drug therapy*
  • Urodynamics / drug effects

Substances

  • Ethanol