[Evaluation of Doppler sonographic criteria for the differentiation of hepatocellular carcinomas and regenerative nodules in patients with liver cirrhosis]

Ultraschall Med. 2002 Apr;23(2):83-90. doi: 10.1055/s-2002-25197.
[Article in German]

Abstract

Aim: In order to improve the differentiation between hepatocellular carcinomas and regenerative nodules in patients with liver cirrhosis, Doppler-sonographic criteria for the tumours were evaluated.

Method: Patients with histologically proven hepatocellular carcinoma (n = 35) and regenerative nodules (n = 10) were investigated by B-mode sonography as well as fundamental and echo-enhanced power-Doppler sonography focusing on specific properties of the tumours. The results were correlated to the histological findings.

Results: Hepatocellular carcinomas and regenerative nodules showed a different contrast behaviour with echo-enhanced power-Doppler sonography. The following features of hepatocellular carcinomas were frequently found: peritumoural signal detection in the early arterial phase, chaotic and centripetal contrast enhancement in the arterial phase, hypervascularization in the capillary phase, and loss of portalvenous blood flow.

Conclusion: Hepatocellular carcinomas and regenerative nodules display different vascularization patterns in the echo-enhanced power-Doppler sonography. These characteristics can be useful for their differential diagnosis.

Publication types

  • Comparative Study

MeSH terms

  • Carcinoma, Hepatocellular / diagnostic imaging*
  • Diagnosis, Differential
  • Humans
  • Liver Cirrhosis / diagnostic imaging*
  • Liver Cirrhosis / pathology
  • Liver Neoplasms / diagnostic imaging*
  • Ultrasonography, Doppler*