Comparison between the role of discontinuities in cardiac conduction and in a one-dimensional hardware model

Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1999 May;59(5 Pt B):5962-9. doi: 10.1103/physreve.59.5962.


In real electrophysiological experiments, irregularities in the extracellular excitation spread are believed to depend on cardiac tissue microstructure. An electronic hardware model was developed to analyze this dependence by placing some inhomogeneities (slow propagation areas) in the medium. The position of such inhomogeneities is correlated with abnormal delays and irregularities measured in signal propagation.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biophysical Phenomena
  • Biophysics
  • Electrophysiology
  • Guinea Pigs
  • Heart Conduction System / physiology*
  • In Vitro Techniques
  • Models, Cardiovascular*
  • Signal Transduction