Abstract
The unrelated GSK-3 and CK1 families stand out among the protein kinases because of their phosphorylated substrate recognition sites. Two papers in the March 22nd issue of Cell highlight the importance of this priming phosphorylation for signal transduction during development.
MeSH terms
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Amino Acid Sequence
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Animals
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Calcium-Calmodulin-Dependent Protein Kinases / metabolism*
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Cytoskeletal Proteins / genetics
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Cytoskeletal Proteins / metabolism*
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Gene Expression Regulation, Developmental / physiology
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Glycogen Synthase Kinase 3
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Molecular Sequence Data
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Signal Transduction / physiology*
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Trans-Activators*
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beta Catenin
Substances
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Cytoskeletal Proteins
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Trans-Activators
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beta Catenin
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Calcium-Calmodulin-Dependent Protein Kinases
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Glycogen Synthase Kinase 3