Signal transduction in development: holding the key

Dev Cell. 2002 Apr;2(4):384-5. doi: 10.1016/s1534-5807(02)00156-9.

Abstract

The unrelated GSK-3 and CK1 families stand out among the protein kinases because of their phosphorylated substrate recognition sites. Two papers in the March 22nd issue of Cell highlight the importance of this priming phosphorylation for signal transduction during development.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Calcium-Calmodulin-Dependent Protein Kinases / metabolism*
  • Cytoskeletal Proteins / genetics
  • Cytoskeletal Proteins / metabolism*
  • Gene Expression Regulation, Developmental / physiology
  • Glycogen Synthase Kinase 3
  • Molecular Sequence Data
  • Signal Transduction / physiology*
  • Trans-Activators*
  • beta Catenin

Substances

  • Cytoskeletal Proteins
  • Trans-Activators
  • beta Catenin
  • Calcium-Calmodulin-Dependent Protein Kinases
  • Glycogen Synthase Kinase 3