Dystonic reaction to propofol attenuated by benztropine (cogentin)

Anesth Analg. 2002 May;94(5):1237-40, table of contents. doi: 10.1097/00000539-200205000-00034.


Neuroexcitatory movements associated with propofol anesthesia are well recognized. Here we report on the successful use of benztropine (2 mg) to abolish abnormal dystonic movements after propofol anesthesia. Forty-five case reports are reviewed, and a treatment strategy for abnormal movements during propofol anesthesia is provided.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anesthetics, Intravenous / adverse effects*
  • Benztropine / therapeutic use*
  • Dystonia / chemically induced*
  • Dystonia / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Muscarinic Antagonists / therapeutic use*
  • Propofol / adverse effects*


  • Anesthetics, Intravenous
  • Muscarinic Antagonists
  • Benztropine
  • Propofol