Complex disease and the new clinical sciences

Science. 2002 Apr 26;296(5568):698-700. doi: 10.1126/science.296.5568.698.


Medical research today is dominated by a genocentric point of view. At the same time, clinical discovery and patient-oriented research have become less common. Here, I suggest that these developments are interdependent, each representing the flip side of an inaccurate view of how clinical advance occurs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Causality
  • Clinical Medicine*
  • Disease* / etiology
  • Humans
  • Research*
  • Skin Diseases / etiology
  • Skin Diseases / genetics
  • Skin Diseases / therapy