Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
, 51 (3), 241-5

How Do Primary Care Physicians Use Long-Term Acid Suppressant Drugs? A Population-Based Analysis of Dutch General Practices

Affiliations
  • PMID: 11978235
Multicenter Study

How Do Primary Care Physicians Use Long-Term Acid Suppressant Drugs? A Population-Based Analysis of Dutch General Practices

G J B Hurenkamp et al. J Fam Pract.

Abstract

Objectives: A considerable proportion of the medication budget of Dutch general practitioners is spent on prescribed long-term acid suppressant drugs. We investigated the magnitude of long-term prescription of acid suppressant drugs in general practice and the frequency and means of confirming the primary working diagnosis.

Study design: We used a retrospective descriptive study of 24 general practices in the Amsterdam region.

Population: We identified those receiving long-term acid suppressant therapy (12 or more weeks/year) from a total of 46,813 patients by extracting data from pharmacy databases.

Outcomes measured: We measured the amount and duration of prescriptions for each medication, indications for prescription, and investigations performed by general practitioners.

Results: Of the 46,813 patients, 922 (2%) received long-term acid suppressant therapy. The duration of prescription varied from 12 weeks in 8% of patients to &gt 52 weeks in 23% of patients (mean = 33 weeks). In 25% of patients, no investigations were performed; 75% of patients underwent endoscopy or ingested a barium meal. The predominant diagnoses in investigated patients were ulcer disease (39%), gastroesophageal reflux disease (49%), and functional dyspepsia (gastritis, normal aspect; 18%). Helicobacter pylori status was available in 29% of patients with ulcer disease. Eradication therapy was reported in 44% of these patients.

Conclusions: Among patients of physicians in general practice in the Amsterdam region, 2% used long-term acid suppressants. Patients with ulcer disease may stop taking acid suppressants after apparent successful H pylori eradication. Tapering strategies must be developed for patients with mild reflux disease or functional dyspepsia.

Similar articles

See all similar articles

Cited by 2 PubMed Central articles

Publication types

MeSH terms

LinkOut - more resources

Feedback