Standardization of pharmacokinetic/pharmacodynamic (PK/PD) Terminology for Anti-Infective Drugs

Int J Antimicrob Agents. 2002 Apr;19(4):355-8. doi: 10.1016/s0924-8579(02)00031-6.

Abstract

Over the last decades, the interest in the relationships between the pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial agents has increased and, therefore, the use of PK/PD indices and expressions has spread widely. The appropriate definition and use of these parameters is a matter of controversy. This paper contains a proposal to use PK/PD expressions for antimicrobial agents and their units in a uniform manner.

MeSH terms

  • Anti-Infective Agents / pharmacokinetics*
  • Anti-Infective Agents / pharmacology*
  • Terminology as Topic*

Substances

  • Anti-Infective Agents