Lyme disease in central Europe

Curr Opin Infect Dis. 2001 Apr;14(2):133-7. doi: 10.1097/00001432-200104000-00004.


Lyme borreliosis is a fascinating disease, the aetiopathology of which is not yet completely known. Different subspecies of Borrelia burgdorferi sensu lato are responsible for the variable clinical course of the disease. Some new cutaneous (alopecia) and ocular (photophobia and retinal vasculitis) manisfestations have been described and the largest prospective study on erythema migrans during pregnancy was published during the last year. Optimal therapy of Lyme borreliosis is still lacking, but doxycycline, amoxicillin, penicillin, and ceftriaxone are recommended most frequently.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Borrelia burgdorferi Group* / classification
  • Borrelia burgdorferi Group* / isolation & purification
  • Europe / epidemiology
  • Humans
  • Lyme Disease / diagnosis
  • Lyme Disease / drug therapy
  • Lyme Disease / epidemiology*
  • Lyme Disease / physiopathology*


  • Anti-Bacterial Agents