Objective: To describe a patient with food intolerance probably contributing to depressive symptoms, intolerance to psychotropic medication and treatment resistance.
Method: The case vignette and investigatory procedures are detailed.
Results: The patient's course improved considerably with an elimination diet.
Conclusions: The prevalence of food intolerance as a contributing factor to depressive disorders requires clarification. Clinicians should be aware of the possible syndrome and that it may be worsened by psychotropic medication.