A case of invasive aspergillosis of the maxillary sinus in an immunocompromised patient is presented. Aspergillosis of the paranasal sinuses is uncommon, however, its incidence has shown a marked increase in number in the recent years. It has been classified into four types: allergic, noninvasive, invasive and fulminant. Immunocompromised patients are particularly at the risk of fulminant invasive aspergillosis. Early diagnosis is essential in order to avoid the high morbidity and mortality associated with the destructive disease and to instigate treatment before irreversible conditions arise.