Blood glucose increases early after stroke onset: a study on serial measurements of blood glucose in acute stroke

Eur J Neurol. 2002 May;9(3):297-301. doi: 10.1046/j.1468-1331.2002.00409.x.


The aim of this study was to evaluate if blood glucose levels change within the first 12 h after stroke onset and to investigate if the degree of change is related to stroke severity, type of stroke, or prognosis. This was a retrospective, descriptive trial based on 445 stroke patients with two blood glucose tests within 12 h of stroke onset and no history of diabetes mellitus. Blood glucose increased in the first 12 h after stroke onset; in mild to moderate stroke from 5.8 to 6.1 mmol/l (P < 0.001) and in severe stroke from 6.2 to 6.7 mmol/l (P < 0.001). In patients who died within 7 days of stroke onset, blood glucose increased from 6.8 to 7.1 mmol/l (P < 0.001). In conclusion, blood glucose increases after the onset of acute stroke and the increase is related to the severity of the stroke.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Aged
  • Aged, 80 and over
  • Blood Glucose / metabolism*
  • Female
  • Humans
  • Hyperglycemia / diagnosis
  • Male
  • Predictive Value of Tests
  • Severity of Illness Index
  • Stroke / blood*
  • Stroke / diagnosis*
  • Stroke / mortality


  • Blood Glucose