SREBPs: Activators of the Complete Program of Cholesterol and Fatty Acid Synthesis in the Liver

J Clin Invest. 2002 May;109(9):1125-31. doi: 10.1172/JCI15593.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Biological Transport / physiology
  • CCAAT-Enhancer-Binding Proteins / genetics
  • CCAAT-Enhancer-Binding Proteins / metabolism*
  • Cholesterol / biosynthesis*
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / metabolism*
  • Fatty Acids / biosynthesis*
  • Gene Expression Regulation*
  • Glucagon / metabolism
  • Humans
  • Insulin / metabolism
  • Liver / metabolism*
  • Mice
  • Mice, Knockout
  • Models, Biological
  • Protein Isoforms
  • Sterol Regulatory Element Binding Protein 1
  • Transcription Factors / metabolism

Substances

  • CCAAT-Enhancer-Binding Proteins
  • DNA-Binding Proteins
  • Fatty Acids
  • Insulin
  • Protein Isoforms
  • SREBF1 protein, human
  • Srebf1 protein, mouse
  • Sterol Regulatory Element Binding Protein 1
  • Transcription Factors
  • Glucagon
  • Cholesterol