Aspirin hepatitis

Am J Dis Child. 1975 Dec;129(12):1433-4. doi: 10.1001/archpedi.1975.02120490045014.

Abstract

Adverse reactions to aspirin, a potentially hepatotoxic drug, are believed to be dose related. This article reviews the medical literature and described two children with aspirin hepatitis. Hepatic dysfunction recurred in one of these patients at salicylate concentrations in serum previously considered nontoxic.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anemia, Sickle Cell / complications
  • Arthritis, Juvenile / complications
  • Arthritis, Juvenile / drug therapy*
  • Aspartate Aminotransferases / blood
  • Aspirin / administration & dosage
  • Aspirin / adverse effects*
  • Aspirin / therapeutic use
  • Chemical and Drug Induced Liver Injury / etiology*
  • Child
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / drug therapy*
  • Male
  • Time Factors

Substances

  • Aspartate Aminotransferases
  • Aspirin