Localisation of the subthalamic nucleus using Radionics Image Fusion and Stereoplan combined with field potential recording. A technical note

Stereotact Funct Neurosurg. 2001;76(2):63-73. doi: 10.1159/000056495.


Subthalamic nucleus stimulation is an effective therapy for alleviating parkinsonian tremor, rigidity and bradykinesia. Although microelectrode recording is said to be essential for accurate targeting, this often prolongs the operation and the multiple recording tracts required may increase the incidence of complications, particularly haemorrhage. We describe a technique for implantation of deep brain electrodes in the subthalamic nucleus using MRI/CT fusion for anatomical localisation followed by bipolar recording of focal field potentials via the implanted stimulating electrode for neurophysiological confirmation of the stimulation site. The technique is effective, safe and requires much less time, and can be used as an alternative method to microelectrode recording.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electric Stimulation Therapy / instrumentation
  • Electric Stimulation Therapy / methods*
  • Electric Stimulation Therapy / statistics & numerical data
  • Humans
  • Magnetic Resonance Imaging / methods
  • Microelectrodes / statistics & numerical data
  • Parkinson Disease / diagnostic imaging
  • Parkinson Disease / surgery
  • Stereotaxic Techniques / instrumentation
  • Stereotaxic Techniques / statistics & numerical data
  • Subthalamic Nucleus / diagnostic imaging
  • Subthalamic Nucleus / physiology
  • Subthalamic Nucleus / surgery*
  • Tomography, X-Ray Computed / methods