Small RNAs in Bacteria: Diverse Regulators of Gene Expression in Response to Environmental Changes

Cell. 2002 Apr 19;109(2):141-4. doi: 10.1016/s0092-8674(02)00717-1.


Bacterial small, untranslated RNAs are important regulators that often act to transmit environmental signals when cells encounter suboptimal or stressful growth conditions. These RNAs help modulate changes in cellular metabolism to optimize utilization of available nutrients and improve the probability for survival.

Publication types

  • Review

MeSH terms

  • Bacteria / genetics*
  • Bacterial Proteins / biosynthesis
  • Bacterial Proteins / genetics
  • Environment*
  • Gene Expression Regulation, Bacterial / genetics*
  • Genes, Regulator / genetics
  • RNA, Bacterial / genetics*
  • RNA, Small Nuclear / genetics*


  • Bacterial Proteins
  • RNA, Bacterial
  • RNA, Small Nuclear