Total knee replacement in haemophilia

Haemophilia. 2002 May;8(3):382-6. doi: 10.1046/j.1365-2516.2002.00604.x.


We believe that total knee replacement (TKR) is a safe and effective procedure for the management of haemophiliac joint arthropathy; however, the increased risk of infection and non-infective complications remain a cause for concern. TKR in haemophilic patients carries with it an increased risk of post-operative infection in comparison to non-haemophiliac patients. Those patients at particular risk are the HIV-positive haemophiliac patients whose CD4 count is less than 200 cells mm-3. The latest techniques have gone a long way to reducing the complication rate and to achieving results that match those of a similar non-haemophiliac population.

Publication types

  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications
  • Arthroplasty, Replacement, Knee* / adverse effects
  • Arthroplasty, Replacement, Knee* / statistics & numerical data
  • Hemarthrosis / prevention & control
  • Hemarthrosis / surgery*
  • Hemophilia A / complications*
  • Hemophilia A / therapy
  • Hemophilia A / virology
  • Humans
  • Treatment Outcome