Metabolic profile of pre-pregnancy, pregnancy and early lactation in multiple lambing Sakiz ewes. 1. Changes in plasma glucose, 3-hydroxybutyrate and cortisol levels

Ann Nutr Metab. 2002;46(2):57-61. doi: 10.1159/000057641.

Abstract

Twenty synchronized Sakiz ewes aged 3-4 years were used in the study. Blood samples were taken once in pre-pregnancy and at the 100th day of pregnancy. At the 120th day of pregnancy and on the 10th day of lactation, blood samples were collected every 2 h for 24 h from only 10 ewes. Plasma cortisol levels were analyzed by radioimmunoassay. Plasma glucose and 3-hydroxybutyrate levels were determined spectrophotometrically. Plasma cortisol level slightly increased at the 100th day of pregnancy, decreased during late pregnancy and continued to decrease during lactation. Plasma glucose and 3-hydroxybutyrate levels were not significantly different during pre-pregnancy, pregnancy and the early lactation periods. In conclusion, the results showed that metabolic disorders such as pregnancy toxaemia did not occur in ewes fed a balanced ration sufficient in energy and protein levels even in a multiple lambing breed of ewes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3-Hydroxybutyric Acid / blood
  • Animals
  • Blood Glucose / analysis
  • Diet / standards
  • Diet / veterinary
  • Female
  • Hydrocortisone / blood*
  • Lactation / metabolism*
  • Pre-Eclampsia / blood
  • Pre-Eclampsia / etiology
  • Pre-Eclampsia / veterinary*
  • Pregnancy
  • Pregnancy, Animal / metabolism*
  • Radioimmunoassay / methods
  • Radioimmunoassay / veterinary
  • Sheep / metabolism
  • Sheep / physiology*

Substances

  • Blood Glucose
  • 3-Hydroxybutyric Acid
  • Hydrocortisone