Intra-operative haemorrhage by blunt versus sharp expansion of the uterine incision at caesarean delivery: a randomised clinical trial

BJOG. 2002 Apr;109(4):448-52. doi: 10.1111/j.1471-0528.2002.01296.x.

Abstract

Objective: To determine whether the method used to expand the uterine incision for caesarean delivery affects the incidence of intra-operative haemorrhage.

Design: A prospective randomised study of women undergoing a low segment transverse caesarean delivery. Participants were assigned to have their uterine incision either sharply or bluntly expanded.

Participants: Between June 1998 and June 2000, 470 women drew assignments to the sharp expansion group and 475 to the blunt group.

Results: The maternal demographics of age, race, nulliparity, and body mass index as well as pre-operative haematocrit were similar between groups. Compared with the blunt group, the estimated blood loss (886 versus 843mL, P = 0.001), change in the mean haematocrit (6.1% versus 5.5%, P = 0.003), incidence of postpartum haemorrhage (13% versus 9%; relative risk = 1.23, 95% CI 1.03, 1.46) and need for a transfusion (2% versus 0.4%; relative risk = 1.65, 95% CI 1.25, 2.21) were significantly greater in the sharp group.

Conclusion: In caesarean delivery, sharply expanding the uterine incision significantly increases intra-operative blood loss and the need for subsequent transfusion.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Loss, Surgical / prevention & control*
  • Cervix Uteri / injuries
  • Cesarean Section / adverse effects*
  • Cesarean Section / methods
  • Female
  • Gestational Age
  • Humans
  • Labor Stage, First
  • Pregnancy
  • Prospective Studies
  • Surgical Instruments
  • Tissue Expansion