Human TLR7 or TLR8 Independently Confer Responsiveness to the Antiviral Compound R-848

Nat Immunol. 2002 Jun;3(6):499. doi: 10.1038/ni0602-499.

Publication types

  • Comment
  • Letter

MeSH terms

  • Adjuvants, Immunologic / pharmacology
  • Animals
  • Antiviral Agents / pharmacology*
  • Cell Line
  • Drosophila Proteins*
  • Humans
  • Imidazoles / pharmacology*
  • Membrane Glycoproteins / drug effects
  • Membrane Glycoproteins / genetics
  • Membrane Glycoproteins / immunology*
  • Mice
  • NF-kappa B / metabolism
  • Receptors, Cell Surface / drug effects
  • Receptors, Cell Surface / genetics
  • Receptors, Cell Surface / immunology*
  • Toll-Like Receptor 7
  • Toll-Like Receptor 8
  • Toll-Like Receptors
  • Transfection

Substances

  • Adjuvants, Immunologic
  • Antiviral Agents
  • Drosophila Proteins
  • Imidazoles
  • Membrane Glycoproteins
  • NF-kappa B
  • Receptors, Cell Surface
  • TLR7 protein, human
  • TLR8 protein, human
  • Toll-Like Receptor 7
  • Toll-Like Receptor 8
  • Toll-Like Receptors
  • resiquimod