Treatment of Scedosporium Apiospermum Brain Abscesses With Posaconazole

Clin Infect Dis. 2002 Jun 15;34(12):1648-50. doi: 10.1086/340522. Epub 2002 May 16.

Abstract

A 41-year-old man with acute lymphoblastic leukemia developed multiple Scedosporium apiospermum brain abscesses. The infection progressed despite neurosurgical drainage and treatment with itraconazole, amphotericin B, and ketoconazole, but the brain abscesses completely resolved after treatment with posaconazole alone.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use*
  • Brain Abscess / drug therapy*
  • Brain Abscess / microbiology
  • Humans
  • Male
  • Mycetoma / drug therapy*
  • Scedosporium* / drug effects
  • Treatment Outcome
  • Triazoles / therapeutic use*

Substances

  • Antifungal Agents
  • Triazoles
  • posaconazole