Sudden death in a patient without heart failure after a single infusion of 200 mg infliximab: does TNF-alpha have protective effects on the failing heart, or does infliximab have direct harmful cardiovascular effects?

Circulation. 2002 May 28;105(21):E183. doi: 10.1161/01.cir.0000017216.41471.df.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Comment

MeSH terms

  • Antibodies, Monoclonal / administration & dosage
  • Antibodies, Monoclonal / adverse effects*
  • Arthritis, Rheumatoid / drug therapy*
  • Clinical Trials, Phase II as Topic
  • Contraindications
  • Death, Sudden / etiology*
  • Electrocardiography
  • Heart / drug effects*
  • Humans
  • Infliximab
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors*
  • Tumor Necrosis Factor-alpha / pharmacology

Substances

  • Antibodies, Monoclonal
  • Tumor Necrosis Factor-alpha
  • Infliximab