Management of medulloepithelioma of the ciliary body with brachytherapy

Am J Ophthalmol. 2002 Jun;133(6):841-3. doi: 10.1016/s0002-9394(02)01432-0.

Abstract

Purpose: To report a case of an adult with a ciliary body mass diagnosed as a medulloepithelioma by fine-needle aspiration, confirmed by tissue biopsy, and successfully treated with brachytherapy.

Design: Interventional case report.

Methods: A 23-year-old white woman presented with a large mass originating in the ciliary body of the left eye. The mass, which measured 6 x 5 x 7.6 mm, was at the upper limits for resection. Treatment with iodine-125 brachytherapy (4,648 cGy) was employed to debulk the mass before eyewall resection.

Results: The elevation of the mass by ultrasonography 5 months after brachytherapy was 3.9 mm with no evidence of growth during the 18-month follow-up period.

Conclusion: We report a case in which a ciliary body medulloepithelioma treated with brachytherapy had a favorable response through 18 months of follow-up after treatment. This is a single case report, and longer follow-up is necessary before treatment efficacy can be fully evaluated.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy, Needle
  • Brachytherapy*
  • Ciliary Body / diagnostic imaging
  • Ciliary Body / pathology
  • Ciliary Body / radiation effects*
  • Female
  • Follow-Up Studies
  • Humans
  • Iodine Radioisotopes / therapeutic use*
  • Neuroectodermal Tumors, Primitive / diagnostic imaging
  • Neuroectodermal Tumors, Primitive / pathology
  • Neuroectodermal Tumors, Primitive / radiotherapy*
  • Treatment Outcome
  • Ultrasonography
  • Uveal Neoplasms / diagnostic imaging
  • Uveal Neoplasms / pathology
  • Uveal Neoplasms / radiotherapy*

Substances

  • Iodine Radioisotopes