Preparation and properties of fluorescein-labelled hyaluronate

Carbohydr Res. 1975 Nov;44(2):251-7. doi: 10.1016/s0008-6215(00)84168-3.


Hyaluronate has been labelled with fluorescein groups by two procedures. Products with degrees of substitution ((d.s.) between 0.05 and 0.001 were obtained. Physico-chemical analysis (viscometry, gel chromatography, and measurements of sedimentation and diffusion coefficients) of the parent compound and the products showed that the labelling procedures caused only a limited degradation of the polysaccharide.

MeSH terms

  • Fluoresceins*
  • Hyaluronic Acid*
  • Ultracentrifugation
  • Viscosity


  • Fluoresceins
  • Hyaluronic Acid