Neurocutaneous melanosis: radiological-pathological correlation

Eur Radiol. 2002 Jun;12(6):1349-53. doi: 10.1007/s00330-001-1195-z. Epub 2001 Nov 20.


We report the case of a young patient with neurocutaneous melanosis (NCM) who presented with temporary aphasia and right hemiparesis followed by progressive coma and death. To our knowledge, this is the first case of this disease examined by CT, MRI, angiography and in which an autopsy was performed to assert the diagnosis with histology. Besides, we discuss differential diagnoses and interest of MRI for early diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiography
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Melanosis / diagnosis*
  • Melanosis / pathology*
  • Neurocutaneous Syndromes / diagnosis*
  • Neurocutaneous Syndromes / pathology*
  • Tomography, X-Ray Computed